Cardiac disease in myotonic dystrophy

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منابع مشابه

Cardiac involvement in myotonic dystrophy

BACKGROUND Myotonic dystrophy (DM) is an inherited progressive muscle disorder caused by defects in muscle proteins. As the incidence of this condition is low, not many are familiar with the multisystem involvement. At times, cardiac disease may even be the predominant manifestation in the form of arrhythmias, conduction defects, and cardiomyopathies. The progression of the disease can lead to ...

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Cardiac involvement in congenital myotonic dystrophy.

Seven young patients (mean age 19 years 8 months) with congenital myotonic dystrophy and with defined symptoms at birth were investigated by electrocardiography and echocardiography. None had cardiovascular symptoms. Electrocardiograms or echocardiograms or both were abnormal in all patients. Atrioventricular and intraventricular conduction defects were the most common electrocardiographic abno...

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Genotype–Phenotype Correlations in Iranian Myotonic Dystrophy Type I Patients

Objectives: Myotonic Dystrophy type I (DM1) is a dominantly inherited disorder with a multisystemic pattern affecting skeletal muscle, heart, eye, endocrine and central nervous system. DM1 is associated with the expansion and instability of CTG repeat in the 3chr('39') untranslated region of the myotonic dystrophy protein kinase (DMPK) gene located on chromosome 19q13.3. The aim of this study w...

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Myotonic dystrophy complicated by peripheral vascular disease.

Case report A 40-year-old man was admitted to a surgical unit with a 3-week history of increasing pain in the right foot. In the past year he had experienced pain in both calves on walking half a mile, and in addition, had been falling frequently, his legs '6;ving way'. He had had bilateral cataract extractions on,., year previously. There was no history of diabetes melitus or medication. He wa...

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Myotonic dystrophy

An unquiet life. Memoirs of a physician and cardiologist. This book is of unusual interest. It is not a history of cardiology in Belfast in the last forty years, though that is touched on in some of its aspects. It is the self-revelation of the remarkable man and physician who revolutionised the practice of cardiology in Belfast, in Ulster, and ultimately the world. He may not have meant it, bu...

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ژورنال

عنوان ژورنال: Cardiovascular Research

سال: 1997

ISSN: 0008-6363

DOI: 10.1016/s0008-6363(96)00163-0